Design and Construction of Ph-Sensitive Drug Delivery System Based on Metal-Organic Framework (MOF) Nanoparticles for Cancer Treatment by Drug Delivery System Containing Curcumin
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چکیده
منابع مشابه
Application of a nanoporous metal organic framework based on iron carboxylate as drug delivery system
In the present study, a nanoporous metal organic framework (MOF) based on iron metal and amino terephthalate ligand MIL-101-NH2-Fe has been used as a carrier for loading and in vitro release of 5-flurouracil (5-FU) anticancer drug. The 5-FU drug loaded MOF was 13 wt % by using thermogravimetric analysis (TGA). The 5-FU release was monitored under physiological condition at 37°C, pH 7.4 in simul...
متن کاملApplication of a nanoporous metal organic framework based on iron carboxylate as drug delivery system
In the present study, a nanoporous metal organic framework (MOF) based on iron metal and amino terephthalate ligand MIL-101-NH2-Fe has been used as a carrier for loading and in vitro release of 5-flurouracil (5-FU) anticancer drug. The 5-FU drug loaded MOF was 13 wt % by using thermogravimetric analysis (TGA). The 5-FU release was monitored under physiological condition at 37°C, pH 7.4 in simul...
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Several plant extracts and phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility or improper molecular size or destruction in gut. Drug delivery system for polyphenolic phytoconstituents (phytosomes) was prepared by complexing polyphenolic phytoconstituents with phospholipid mainly phosphatidylcholine wh...
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Introduction: Osteosarcoma is one of the cancers that current treatment strategies using chemotherapy drugs have not been very successful due to multiple drug resistance and harmful side effects. The use of nano-niosomal systems in the delivery of paclitaxel is one of the attractive approaches to overcome these limitations. paclitaxel is a powerful anticancer agent used in the treatment of many...
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ژورنال
عنوان ژورنال: Journal of Shahid Sadoughi University of Medical Sciences
سال: 2020
ISSN: 2228-5733,2228-5741
DOI: 10.18502/ssu.v28i9.4774